diff --git a/esphome/components/sen5x/sensor.py b/esphome/components/sen5x/sensor.py
index 489fda8335..392510e417 100644
--- a/esphome/components/sen5x/sensor.py
+++ b/esphome/components/sen5x/sensor.py
@@ -119,7 +119,7 @@ CONFIG_SCHEMA = (
                 device_class=DEVICE_CLASS_PM10,
                 state_class=STATE_CLASS_MEASUREMENT,
             ),
-            cv.Optional(CONF_AUTO_CLEANING_INTERVAL): cv.time_period_in_seconds_,
+            cv.Optional(CONF_AUTO_CLEANING_INTERVAL): cv.update_interval,
             cv.Optional(CONF_VOC): sensor.sensor_schema(
                 icon=ICON_RADIATOR,
                 accuracy_decimals=0,
diff --git a/tests/test5.yaml b/tests/test5.yaml
index 6b64ef2d15..cb4b559b06 100644
--- a/tests/test5.yaml
+++ b/tests/test5.yaml
@@ -489,6 +489,7 @@ sensor:
       offset: 0
       normalized_offset_slope: 0
       time_constant: 0
+    auto_cleaning_interval: 604800s
     acceleration_mode: low
     store_baseline: true
     address: 0x69