diff --git a/esphome/components/sen0501/__init__.py b/esphome/components/sen0501_i2c/__init__.py
similarity index 100%
rename from esphome/components/sen0501/__init__.py
rename to esphome/components/sen0501_i2c/__init__.py
diff --git a/esphome/components/sen0501/sen0501.cpp b/esphome/components/sen0501_i2c/sen0501_i2c.cpp
similarity index 89%
rename from esphome/components/sen0501/sen0501.cpp
rename to esphome/components/sen0501_i2c/sen0501_i2c.cpp
index f5b3c06b6b..a4a96eec4e 100644
--- a/esphome/components/sen0501/sen0501.cpp
+++ b/esphome/components/sen0501_i2c/sen0501_i2c.cpp
@@ -1,11 +1,11 @@
-#include "sen0501.h"
+#include "sen0501_i2c.h"
 #include "esphome/core/log.h"
 #include "esphome/core/hal.h"
 
 namespace esphome {
-namespace sen0501 {
+namespace sen0501_i2c {
 
-static const char *const TAG = "sen0501";
+static const char *const TAG = "sen0501_i2c";
 
 // Device Address
 static const uint8_t SEN050X_DEFAULT_DEVICE_ADDRESS = 0x22;
@@ -29,7 +29,7 @@ static const uint16_t REG_ATMOSPHERIC_PRESSURE = 0x0018;
 
 // PUBLIC
 
-void Sen0501Component::setup() {
+void Sen0501_i2cComponent::setup() {
   ESP_LOGCONFIG(TAG, "Setting up sen0501...");
   uint8_t product_id_first_byte;
   if (!this->read_byte(REG_PID, &product_id_first_byte)) {
@@ -55,7 +55,7 @@ void Sen0501Component::setup() {
   }
 }
 
-void Sen0501Component::update() {
+void Sen0501_i2cComponent::update() {
   this->read_temperature_();
   this->read_humidity_();
   this->read_uv_intensity_();
@@ -63,7 +63,7 @@ void Sen0501Component::update() {
   this->read_atmospheric_pressure_();
 }
 
-void Sen0501Component::dump_config() {
+void Sen0501_i2cComponent::dump_config() {
   ESP_LOGCONFIG(TAG, "DFRobot Environmental Sensor - sen0501:");
   LOG_I2C_DEVICE(this);
   switch (this->error_code_) {
@@ -89,11 +89,11 @@ void Sen0501Component::dump_config() {
   LOG_SENSOR("  ", "Elevation", this->elevation_);
 }
 
-float Sen0501Component::get_setup_priority() const { return setup_priority::DATA; }
+float Sen0501_i2cComponent::get_setup_priority() const { return setup_priority::DATA; }
 
 // PROTECTED
 
-void Sen0501Component::read_temperature_() {
+void Sen0501_i2cComponent::read_temperature_() {
   if (this->temperature_ == nullptr)
     return;
   uint8_t buffer[2];
@@ -104,7 +104,7 @@ void Sen0501Component::read_temperature_() {
   this->temperature_->publish_state(temp);
 }
 
-void Sen0501Component::read_humidity_() {
+void Sen0501_i2cComponent::read_humidity_() {
   if (this->humidity_ == nullptr)
     return;
   uint8_t buffer[2];
@@ -115,7 +115,7 @@ void Sen0501Component::read_humidity_() {
   this->humidity_->publish_state(humidity);
 }
 
-void Sen0501Component::read_uv_intensity_() {
+void Sen0501_i2cComponent::read_uv_intensity_() {
   if (this->uv_intensity_ == nullptr)
     return;
   uint8_t buffer[2];
@@ -141,7 +141,7 @@ void Sen0501Component::read_uv_intensity_() {
   this->uv_intensity_->publish_state(ultra_violet);
 }
 
-void Sen0501Component::read_luminous_intensity_() {
+void Sen0501_i2cComponent::read_luminous_intensity_() {
   if (this->luminous_intensity_ == nullptr)
     return;
   uint8_t buffer[2];
@@ -152,7 +152,7 @@ void Sen0501Component::read_luminous_intensity_() {
   this->luminous_intensity_->publish_state(luminous);
 }
 
-void Sen0501Component::read_atmospheric_pressure_() {
+void Sen0501_i2cComponent::read_atmospheric_pressure_() {
   if (this->atmospheric_pressure_ == nullptr && this->elevation_ == nullptr)
     return;
   uint8_t buffer[2];
@@ -166,5 +166,5 @@ void Sen0501Component::read_atmospheric_pressure_() {
   }
 }
 
-}  // namespace sen0501
+}  // namespace sen0501_i2c
 }  // namespace esphome
diff --git a/esphome/components/sen0501/sen0501.h b/esphome/components/sen0501_i2c/sen0501_i2c.h
similarity index 92%
rename from esphome/components/sen0501/sen0501.h
rename to esphome/components/sen0501_i2c/sen0501_i2c.h
index 8ff10b15e6..175805d969 100644
--- a/esphome/components/sen0501/sen0501.h
+++ b/esphome/components/sen0501_i2c/sen0501_i2c.h
@@ -8,9 +8,9 @@
 // https://github.com/DFRobot/DFRobot_EnvironmentalSensor
 
 namespace esphome {
-namespace sen0501 {
+namespace sen0501_i2c {
 
-class Sen0501Component : public PollingComponent, public i2c::I2CDevice {
+class Sen0501_i2cComponent : public PollingComponent, public i2c::I2CDevice {
  public:
   void set_temperature(sensor::Sensor *temperature) { this->temperature_ = temperature; }
   void set_humidity(sensor::Sensor *humidity) { this->humidity_ = humidity; }
@@ -48,5 +48,5 @@ class Sen0501Component : public PollingComponent, public i2c::I2CDevice {
   } error_code_{NONE};
 };
 
-}  // namespace sen0501
+}  // namespace sen0501_i2c
 }  // namespace esphome
diff --git a/esphome/components/sen0501/sensor.py b/esphome/components/sen0501_i2c/sensor.py
similarity index 94%
rename from esphome/components/sen0501/sensor.py
rename to esphome/components/sen0501_i2c/sensor.py
index 3379503fbd..553a413a5a 100644
--- a/esphome/components/sen0501/sensor.py
+++ b/esphome/components/sen0501_i2c/sensor.py
@@ -33,15 +33,15 @@ CONF_ELEVATION = "elevation"
 
 DEPENDENCIES = ["i2c"]
 
-sen0501_ns = cg.esphome_ns.namespace("sen0501")
-Sen0501Component = sen0501_ns.class_(
-    "Sen0501Component", cg.PollingComponent, i2c.I2CDevice
+sen0501_ns = cg.esphome_ns.namespace("sen0501_i2c")
+Sen0501_i2cComponent = sen0501_ns.class_(
+    "Sen0501_i2cComponent", cg.PollingComponent, i2c.I2CDevice
 )
 
 CONFIG_SCHEMA = (
     cv.Schema(
         {
-            cv.GenerateID(): cv.declare_id(Sen0501Component),
+            cv.GenerateID(): cv.declare_id(Sen0501_i2cComponent),
             cv.Optional(CONF_TEMPERATURE): sensor.sensor_schema(
                 unit_of_measurement=UNIT_CELSIUS,
                 icon=ICON_THERMOMETER,